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Volume 10, Issue 3

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www.AbbysHealthFood.com | # 51| Page 3 Berberine is a rising star in the herbal world. This bright yellow compound is found in several plants, such as barberry, goldenseal, and Oregon grape. While it's only recently become popular in the United States, it's been used for centuries. One of its greatest strengths is its versatility; berberine shows promise for a wide range of health benefits. What does the science say about berberine? Cardiovascular Health. Berberine is best known for its cardiovascular benefits. It's been shown in multiple human studies to help maintain cholesterol levels already in a healthy range. Consider this impressive finding: A review of 11 studies, enrolling nearly 1,000 volunteers, found berberine supported healthy levels of total cholesterol, triglycerides, LDL (bad) cholesterol, and HDL (good cholesterol) to a degree the researchers called "remarkable." Blood Sugar Support. Berberine has also been shown to support blood sugar balance in human volunteers. How? Several ways. This yellow pigment blocks the enzymes needed to break down and digest carbohydrates. It also activates the enzyme AMPK, which acts as a metabolic master switch. Finally, berberine supports healthy insulin sensitivity, which helps your body efficiently process sugar. ,, Weight Management. Berberine may also be a useful tool to support weight management, in conjunction with a healthy diet and exercise, of course. , Researchers theorize that it works by helping maintain a good balance of gut bacteria, which have a surprising influence on body weight. Gut and Liver Health. In addition to promoting healthy gut bacteria populations, berberine also has been shown to support the gut mucosa of mice, suggesting it may have multiple gut-defending actions. Berberine also supported liver health in rats by altering gene expression. One thing to keep in mind when looking for a berberine supplement is that some species of barberry (such as Nevin's barberry and Island barberry) are endangered, as is goldenseal and Oregon grape. , That's one of the reasons we recommend WellBetX® Berberine from Natural Factors, which is sustainably extracted from non-endangered barberry (Berberis vulgaris). We also like that the dose is the same as that used in clinical research on insulin sensitivity and weight loss. WellBetX Berberine is free of artificial colors, preservatives, sugar, artificial sweeteners, salt, gluten, GMOs, and common allergens such as dairy, wheat, yeast, soy, corn, egg, fish, shellfish, and tree nuts. Plus, it's suitable for vegetarians and vegans. Whether you're looking for help maintaining your cholesterol and/or blood sugar within healthy limits, trying to stay trim, or taking care of your gut and liver health, we suggest you give Natural Factors WellBetX Berberine a try. References 1 Dong H, et al. Planta Med. 2013 Apr;79(6):437-46. https://pubmed.ncbi.nlm.nih.gov/23512497/ 2 Yin J, Ye J, Jia W. Acta Pharm. 2012 Aug;2(4):327-34. https://www.sciencedirect.com/science/ article/pii/S2211383512000871 3 Yin, 2012. 4 Yin, 2012. 5 Yang J, et al. Evid Based Complement Alternat Med. 2012;2012:363845. https://www.ncbi.nlm. nih.gov/pmc/articles/PMC3310165/ 6 Liu L. Mol Cell Endocrinol. 2010 Apr 12;317(1-2):148-53. https://pubmed.ncbi.nlm.nih. gov/20036710/ 7 Zhang X, et al. Sci Rep. 2015 Sep 23;5:14405. https://www.nature.com/articles/srep14405 8 Hu Y, et al. Phytomedicine. 2012 Jul 15;19(10):861-67. https://www.sciencedirect.com/science/ article/abs/pii/S0944711312001870 9 Yang, 2012. 10 Zhang, 2015. 11 Wang X, et al. PLoS One. 2015 Jul 30;10(7):e0134044. https://pdfs.semanticscholar.org/5794/ a0d615dbae9c6bbdc818ae11906bd880d1ed.pdf?_ga=2.171788070.720914507.1638387390- 1725902450.1638387390 12 Yuan X, et al. J Transl Med. 2015 Jan 27;13:24. https://translational-medicine.biomedcentral. com/articles/10.1186/s12967-015-0383-6 13 https://wildlife.ca.gov/Conservation/Plants/Endangered/Berberis-nevinii 14 https://ecos.fws.gov/ecp/species/5197

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