Issue link: http://cp.revolio.com/i/924515
"heat shock proteins" in response to stress caused by the infection of the bacteria. Some of these heat shock proteins mimic pancreatic glutamic acid decarboxylase, or GAD. The MAP does this in order to hide from the body's immune system. Confusion ensues and the body starts producing antibodies against its own pancreatic tissue. Testing for anti- GAD antibodies is one way to confirm type 1 diabetes. GAD is responsible for the synthesis of GABA in the body, an inhibitory neurotransmitter that calms the nervous system and may reduce anxiety. Supplemental GABA may be a specifically important option for people with type 1 diabetes. The link between GAD, type 1 diabetes, and the particular MAP heat shock protein was established as early as 1990 by a study published in The Lancet, volume 336, No.8715. Disproportionate amounts of MAP have been found in the blood of type 1 diabetics versus healthy controls AND versus type 2 diabetics. Antibodies against MAP bacteria proteins in type 1 diabetics have been found in multiple studies out of Italy and in one study out of Sardinia called the TRIGR study. In fact, 7 out of 8 studies on MAP and type 1 diabetes showed a significant association between the two. It is interesting to understand why the 8th study did not find a link between MAP bacteria and type 1 diabetes. The 8th study came out of India and some explanations were put forward as to why they did not find an association, such as, possible cross protection from Mycobacterium avium ssp. paratuberculosis due to commonplace vaccination for regular tuberculosis, high incidences of vegetarianism, or the compulsory boiling of milk that Indians often do before consuming it. Boiling may destroy MAP better than pasteurization. To avoid contracting too much MAP bacteria consider consuming animal foods less often, buy from local dairies with more quality control, or buy raw milk and boil it yourself or take a probiotic with it. Also, after handling raw meat, be sure to wash your hands and arms with hot soapy water for at least 3 minutes and cook your meat until well done. If you absolutely must have your steak bloody or medium temperature, then consuming natural antimicrobials such as berberine at the same time, wouldn't be a bad idea. In fact, whenever primates consume meat, they always consume bitter leaves with it to prevent infection and to aid digestion. Cow's Milk Many studies indicate an association between early exposure to cow's milk in infants and type 1 diabetes. The TRIGR study mentioned above furthered this research and compared regular cows-milk based infant formula versus hydrolyzed cows-milk based infant formula and showed a lower incidence of type 1 diabetes in the hydrolyzed group. However, this is only half the story. Around 2,000 or more years ago a mutation in Northern European cows caused them to produce the protein casein A-1 in their milk instead of the usual casein A-2. Casein A-1 is more difficult to digest than casein A-2 causing more bloating and upset stomach. However, once it is digested, casein A-1 turns into a lectin-like protein called beta- casomorphin-7. This protein pries open the gut, enters the blood stream, and attaches to the beta cells of the pancreas, causing the immune system to attack them, another case of mistaken identity. Products like Restore, and other leaky gut supportive products may help mitigate breaches of the intestinal wall by lectins, plus, breakdown in tight junction proteins in the kidneys of type 1 diabetics has been shown in studies and Restore may possibly improve tight junction function in the kidneys also. According to a study published in the Nutrition & Diabetes journal in 2017, "A1 β-casein consumption correlates significantly with type 1 diabetes incidence and shows a stronger correlation than does milk consumption per se." To ensure you or your children are not consuming casein A-1 at all, either avoid dairy altogether, or choose goat, yak, sheep, camel, buffalo, or donkey dairy products instead of cow dairy products. In addition, you may ask your dairy provider whether their cows are predominantly A-1 producing or predominantly A-2 producing, or whether they are Holstein, Friesian, Ayrshire, and British Shorthorn cows (A-1) or Jersey, Guernsey, Brown Swiss, or Belgian Blues (A- 2). Abby and our grocery manager Jennifer Butler have assured me personally that the raw milk Abby's sells comes from Jersey cows! Genetics A genetic polymorphism in humans on the gene called SLC11A1 may make a person more at-risk for type 1 diabetes. SLC11A1 activates macrophages that engulf pathogens such as MAP. Therefore, if a person has a mutation on this gene, then they are more susceptible to Mycobacterium avium paratuberculosis infections. Page 42 | Abby's Magazine - www.AbbysMag.com