Volume 4 Issue 6

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Abby's Magazine - Volume 4 Issue 6| Page 9 Abstract An bio cs administered in low doses have been widely used as growth promoters in the agricultural industry since the 1950s, yet the mechanisms for this effect are unclear. Because an microbial agents of different classes and varying ac vity are effec ve across several vertebrate species, we proposed that such sub-therapeu c administra on alters the popula on structure of the gut microbiome, as well as its metabolic capabili es. A model of adiposity was generated by giving sub- therapeu c an bio c therapy to young mice and evaluated changes in the composi on and capabili es of the gut microbiome. Administra on of sub-therapeu c an bio c therapy increased adiposity in young mice and increased hormone levels related to metabolism. Substan al taxonomic changes in the microbiome was observed, changes in copies of key genes involved in the metabolism of carbohydrates to short-chain fa y acids, increases in colonic short-chain fa y acid levels, and altera ons in the regula on of hepa c metabolism of lipids and cholesterol. In this model, we demonstrate the altera on of early-life mouse metabolic homeostasis through an bio c manipula on. Antibiotics in early life alter the mouse colonic microbiome and adiposity The Ultimate Shake † Helps curb appetite by helping you feel full. * These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease. The Renew Life® Skinny Gut Ultimate Shake has everything you want in a healthy protein shake and nothing that you don't. It's USDA Organic and grain free, and comes in delicious, natural vanilla or chocolate flavors. You'll enjoy the convenience of all these ingredients in one great shake that promotes healthy gut balance, helps build muscle, and curbs appetite. * † ✔ Certifi ed Organic ✔ Grain Free ✔ Vegan ✔ 20 grams Protein ✔ 10 grams Fiber ✔ Vitamins & Minerals ✔ Digestive Enzymes ✔ Antioxidant Blend ✔ Gluten & Dairy Free ✔ Low Fat & Low Calorie ✔ Delicious Taste ✔ No Artifi cial Ingredients ✔ No Preservatives ✔ No GMOs ✔ No Added Sugar ✔ 10 Billion Probiotic Cultures RNL-7158 ALSO TRY Extra Care Probiotic 50 Billion

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