Issue link: http://cp.revolio.com/i/602310
In the past, degeneration of brain cells (neurons) seen in AD was considered to be because of aging alone; however, new and emerging studies have seen that AD and cardiovascular disease (CVD) share many characteristics and triggers. This led to the conclusion that addressing cardiovascular issues can significantly reduce the risk of AD. We have seen that in the featured cases today. In Case 1, the patient has a history of heart disease, undergoing 3 bypass surgeries. Now he has brain atrophy and memory problems. In Case 2, the patient has an ear crease (sign of CVD), hypertension and heavy metal toxicity (which can affect cardiovascular function). Now she has severe memory loss. So using early markers of CVD can also alert you to a possible risk for AD. Later on we will see how CVD can affect brain and cognitive function. --- Signs of Alzheimer's Disease --- In addition to CVD markers, the following are also early signs of AD: • Ear ringing - If you have ear ringing but have no hypertension or sinus problems, this may signal hardening of the arteries (atherosclerosis) especially near the brain. • Balance issues – If you easily lose your balance (fall down easily), this may also be a sign of early AD • Short-term memory loss – Many AD patients first experience sporadic memory loss. For example, they can't remember where they left their keys. As AD gets worse, they may eventually not recognize their own family members. • No sense of direction or time – In later stages of AD, patients often get confused as to what time it is or their location. • Language/Speech issues – Because of damage to the hippocampus, AD patients may start to have difficulty recognizing words and may become confused. Due to this, they may lack the desire to read and also have trouble articulating words Hypoxia and Ischemia Increases Amyloid beta deposits, Lowers Acetylcholine, Causes Oxidative Damage to Neurons There is a great deal of evidence to suggest that the lack of blood flow to the brain (cerebral ischemic episodes) may be the trigger that causes loss of neurons and initiates the cognitive changes seen in Alzheimer's disease. The hypoxic condition (lack of oxygen) caused by ischemia leads to increased amyloid beta production and plaque formation in central neurons. Hypoxia also leads to oxidative stress that causes damage to neurons. Brain autopsies of Alzheimer's patients discovered substantial oxidative damage caused by free radicals (Sources: Molecular Neurobiology. 2013; 48:500-515; Ann NY Acad Sci. 2005; 1043:545-52). Page 20 | Abby's Magazine - www.AbbysMag.com